Top 5 Female Anime Protagonists

The world of anime has given audiences some of the most memorable and inspiring female/female presenting protagonists. Their stories continue to resonate with audiences worldwide. These five characters have earned their spots by showcasing their courage, resilience, and empathy. Ranging from “magical girl” to “fashion icons,” here is a list of the top five female anime protagonists who have become cultural icons and challenge stereotypes.

5. Kagome Higurashi from "Inuyasha"

kagome in top female anime protagonists

Inuyasha follows 15-year-old Kagome Higurashi as she is transported to the Sengoku period after falling into a well in her family shrine, where she meets the half-dog demon, Inuyasha. After the Shikon Shikon Jewel re-emerges from deep inside Kagome’s body, she inadvertently shatters it into dozens of fragments that scatter across Japan. Inuyasha and Kagome set out to recover Jewel’s fragments with the help of friends they meet along the way. They must prevent it from falling into the hands of the evil half-demon, Naraku. 

Kagome ranks in the top five due to her strong sense of compassion. Despite being thrown into a dangerous, unfamiliar world, Kagome faces threats head-on. Whether it’s fighting demons or protecting her friends, she shows tremendous bravery throughout the series. Finally, Kagome is a relatable character to watchers as they see her juggle school, family responsibilities, and an epic quest, all while navigating complex emotions, which makes her a character anyone can connect with.

4. Nana Osaki from "NANA"

Nana O

NANA is an anime and manga series written by Ai Yazawa that follows two young women who coincidently are both named “Nana.” The two fatefully meet on a train headed to Tokyo. Although polar opposite in personalities and life goals, they quickly become friends and become roommates. Nana Osaki’s (referred to as Nana or Nana O) dream is to pursue her career as a punk rock artist with her band, Black Stones (Blast). Nana Komatsu (referred to as Hachi) has no definite career goal but is often seeking love and validation from men. The show follows their relationship with tough topics that the audience encounters in the real world: career, love, friendships, heartbreak, and personal growth. 

Nana Osaki makes it to the top five female anime protagonists due to her strong-will and determination to launch her career. She is faithful to her band members and friends, including Hachi. Despite having a troubled past, Nana is resilient and focused. Nana is a true example of pursuing one’s dreams in the face of adversity. Additionally, Nana’s iconic style which is heavily influenced by the fashion brand, Vivienne Westwood, not only cements her position in the top 5, but also inspires audiences to create their own unique sense of fashion style.  

3. Nezuko Kamado from "Demon Slayer: Kimetsu No Yaiba"

Demon Slayer: Kimetsu No Yaiba nezuko top anime female protagonists

Demon Slayer: Kimetsu No Yaiba is an anime series set in Taisho-era Japan that follows the story of a young boy named Tanjiro Kamado. After Tanjiro’s family is brutally attacked and murdered by demons, only one member of his family survives. Nezuko instead becomes a demon herself. The storyline revolves around Tanjiro and his determination to avenge his family as well as find a cure to turn Nezuko back into a human. 

Nezuko earns her spot in the top five for her representation of the power of family bond and a sense of willpower. Despite being turned into a demon, she is able to retain her love for humanity and is constantly protecting her brother. She shows a great sense of willpower as she refuses to eat any human being. Many of the viewers can relate to the bond she has with her brother. Nezuko is willing to fight and protect him at all costs; including bring harm to herself. Her loyalty and determination to fight her demonic instincts, makes her a unique and inspiring character. 

2. Frieren from "Frieren: Beyond Journey’s End"

Frieren - top female anime protagonists

Frieren: Beyond Journey’s End is an anime series that follows the life of an elven mage, Frieren, who was part of a heroic group that defeated the Demon-King in a decade-long journey. This particular protagonist is an elf who has an extremely long life span who outlives the humans she has interacted with. After 50 years since the defeat of the Demon King, Frieren embarks on a new journey with her apprentice, Fern, and a warrior named Stark. The plot unfolds as the audience witnesses Frieren explore human emotions, and recalling memories of her past. 

Although Frieren appears to be young, she is over 1,000 years old. Also, shas become one of the greatest mages that have ever lived. Frieren is powerful and often regarded by many. Her remarkable qualities place her in the top female anime protagonists because of her knowledge and power. Not only is she a great mage, but she is also open minded. Throughout the show, she reveals her self-discovery and growth. Frieren’s dedication to her craft demonstrates that true joy can be found in pursuing one’s passion. Her commitment to constantly learning, inspires audiences to strive for excellence and invest wholeheartedly in what they love. 

1. Usagi Tsukino from "Sailor Moon"

sailor moon

Sailor Moon is an anime and manga that follows the adventures of a teenage girl named Usagi Tsukino. Usagi, like many teens, is clumsy, ordinary, and somewhat unmotivated. One day, she meets a talking black cat named Luna. Luna reveals that Usagi is actually a magical warrior named Sailor Moon. Throughout the series, Usagi meets the other Sailor Guardians. Their mission is to protect against threats on Earth and the universe. 

Although Usagi may seem ordinary, she is representative of compassion and bravery to young girls. She constantly sticks up for her friends and demonstrates an immense willpower to fight against evil. Usagi’s willingness to protect her friends and loved ones at any costs, is a trait that resonates deeply with audiences. Usagi shows that vulnerability can oftentimes be a source of strength. Her growth from a clumsy, bratty teen into a compassionate leader inspires young viewers, emphasizing growth and the power of selflessness. 

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